• 介紹： Colchicine is a tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs)

• 熔點： 150-160℃

• 比旋光度： (CHCl3)-121

• 外觀： 白色粉末

• 溶解性： Soluble  in  DMSO、H2O

• 敏感性： 對光敏感,易吸潮

• 儲存條件： 2-8℃

• 用途： Functions by binding to tubulin and arresting cell division at m

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

• 9. [IF=7.9] Tian Lan et al."Paeoniflorin promotes PPARγ expression to suppress HSCs activation by inhibiting EZH2-mediated histone H3K27 trimethylation."PHYTOMEDICINE".2024 Jun;128:155477

• 8. [IF=6.1] Guangwen Shu et al."Ergothioneine suppresses hepatic stellate cell activation via promoting Foxa3-dependent potentiation of the Hint1/Smad7 cascade and improves CCl4-induced liver fibrosis in mice."Food & Function.2023 Nov;:

• 7. [IF=3.3] Piao Huiqing et al."Ternary Deep Eutectic Solvents System of Colchicine, 4-Hydroxyacetophenone, and Protocatechuic Acid and Characterization of Transdermal Enhancement Mechanism."AAPS PHARMSCITECH.2023 Dec;24(8):1-15

• 6. [IF=7.9] Tingting Qin et al."Geniposide alleviated bile acid-associated NLRP3 inflammasome activation by regulating SIRT1/FXR signaling in bile duct ligation-induced liver fibrosis."PHYTOMEDICINE.2023 Sep;118:154971

• 5. [IF=16.6] Fan Shengjie et al."Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions."Nature Communications.2023 Jun;14(1):1-23

• 4. [6.51] Meng Chen et al."Deuterated colchicine liposomes based on oligomeric hyaluronic acid modification enhance anti-tumor effect and reduce systemic toxicity."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2022 Dec;:122578

• 3. [IF=9.229] Qing-Shan Liu et al."Novel Beta-Tubulin-Immobilized Nanoparticles Affinity Material for Screening β-Tubulin Inhibitors from a Complex Mixture."Acs Appl Mater Inter. 2017;9(7):5725–5732

• 2. 范素芳, 馬俊美, 劉茁,等. 高效液相色譜-串聯(lián)質(zhì)譜測定食品中15種有毒生物堿[J]. 食品科學(xué), 2018, 39(22):290-295.

• 1. 李培寧 陳秀娟 江漪 等. 3種化合物在UV誘導(dǎo)下對CHL細(xì)胞染色體畸變作用[J]. 日用化學(xué)工業(yè) 2019 49(006):377-380 387.

輸入產(chǎn)品批號：

本計算器可幫助您計算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *