• 介紹：

   Dioscin(CCRIS 4123; Collettiside III)是天然的植物來源的甾體皂苷，針對多種癌細(xì)胞有較好的抗癌活性。

• 熔點(diǎn)： 294-296 °C

• 比旋光度： D13 -115° (c = 0.373 in ethanol)

• 外觀： 白色或微黃的結(jié)晶性粉末

• 溶解性： DMSO  :  ≥  100  mg/mL  (115.07  mM)

• 敏感性： 易吸潮

• 儲存條件： 2-8℃

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

• 42. [3.8] Zhang Chenxu et al."Integrating network pharmacology and experimental validation to decipher the pharmacological mechanism of DXXK in treating diabetic kidney injury."Scientific Reports.2024 Sep;14(1):1-15

• 41. [IF=4.8] Chengfei Zhang et al."Dioscin Ameliorates Experimental Autoimmune Thyroiditis via the mTOR and TLR4/NF-κB Signaling."Drug Design Development and Therapy.

• 40. [IF=6.208] Weipeng Wang et al."The Functional Characterization of DzCYP72A12-4 Related to Diosgenin Biosynthesis and Drought Adaptability in Dioscorea zingiberensis."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2023 Jan;24(9):8430

• 39. [3.614] Gaodan Liu et al."Extraction and identification of steroidal saponins from Polygonatum cyrtonema Hua using natural deep eutectic solvent-synergistic quartz sand assisted extraction method."JOURNAL OF SEPARATION SCIENCE.2023 Feb;:2200823

• 38. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199

• 37. [IF=4.412] Feng Su et al."Study of Chemical Compositions and Anticancer Effects of Paris polyphylla var. Chinensis Leaves."MOLECULES. 2022 Jan;27(9):2724

• 36. [IF=5.753] Jianghong Gao et al."Molecular Cloning and Functional Characterization of a Sterol 3-O-Glucosyltransferase Involved in Biosynthesis of Steroidal Saponins in Trigonella foenum-graecum.."Front Plant Sci. 2021 Dec;12:809579-809579

• 35. [IF=2.998] Wang Zhijuan et al.Preparation of dioscin from Trigonella foenum-graecum by foam separation–preparative high-performance liquid chromatography.European Food Research And Technology.2021 Nov 24

• 34. [IF=7.658] Yu-Xi Liu et al.Inhibition of Src/STAT3 signaling-mediated angiogenesis is involved in the anti-melanoma effects of dioscin.Pharmacol Res. 2022 Jan;175:105983

• 33. [IF=2.055] Jieru Han et al."Preventive effect of dioscin against monosodium urate-mediated gouty arthritis through inhibiting inflammasome NLRP3 and TLR4/NF-κB signaling pathway activation: an in vivo and in vitro study."J Nat Med-Tokyo. 2021 Jan;75(1):37-47

• 32. [IF=2.1] Yuyan Zhang et al."Tanshinone I and simvastatin inhibit melanoma tumour cell growth by regulating poly (ADP ribose) polymerase 1 expression."Mol Med Rep. 2021 Jan;23(1):1-1

• 31. [IF=2.289] Zhou Shun et al."Anthelmintic efficacy of natural saponins against Gyrodactylus kobayashii in goldfish (Carassius auratus) and their 3D-QSAR analysis."Parasitol Res. 2021 Mar;120(3):1143-1150

• 30. [IF=2.311] Yu?Xi Liu et al."Inhibiting the Src/STAT3 signaling pathway contributes to the anti?melanoma mechanisms of dioscin."Oncol Lett. 2020 Mar;19(3):2508-2514

• 29. [IF=3.412] Shun Zhou et al."Antiparasitic Efficacy of Herbal Extracts and Active Compound Against Gyrodactylus kobayashii in Carassius auratus."Front Vet Sci. 2021; 8: 665072

• 28. [IF=4.242] Shun Zhou et al."Anthelmintic efficacy of 35 herbal medicines against a monogenean parasite, Gyrodactylus kobayashii, infecting goldfish (Carassius auratus)."Aquaculture. 2020 May;521:734992

• 27. [IF=4.466] Yao Tan et al."Multiomics Integrative Analysis for Discovering the Potential Mechanism of Dioscin against Hyperuricemia Mice."J Proteome Res. 2021;20(1):645–660

• 26. [IF=4.952] Qun Yu et al."Enhancing the antityrosinase activity of saponins and polyphenols from Asparagus by hot air coupled with microwave treatments."Lwt Food Sci Technol. 2020 Apr;124:109174

• 25. [IF=5.645] Lixiu Hou et al."Geographical variations in fatty acid and steroid saponin biosynthesis in Dioscorea zingiberensis rhizomes."Ind Crop Prod. 2021 Oct;170:113779

• 24. [IF=5.923] Lixiu Hou et al."Genome-Wide Identification of CYP72A Gene Family and Expression Patterns Related to Jasmonic Acid Treatment and Steroidal Saponin Accumulation in Dioscorea zingiberensis."Int J Mol Sci. 2021 Jan;22(20):10953

• 23. [IF=2.998] Lei Lei et al."Preparation of diosgenin from Dioscorea zingiberensis C. H. Wright by stepwise biocatalysis-foam separation-preparative high-performance liquid chromatography (P-HPLC)."Eur Food Res Technol. 2018 Aug;244(8):1447-1452

• 22. [IF=3.998] Yang Rui et al."Dioscin relieves endotoxemia induced acute neuro-inflammation and protect neurogenesis via improving 5-HT metabolism."Sci Rep-Uk. 2017 Jan;7(1):1-13

• 21. [IF=4.759] Mengshun Liu et al."Folding fan mode counter-current chromatography offers fast blind screening for drug discovery. Case study: Finding anti-enterovirus 71 agents from Anemarrhena asphodeloides."J Chromatogr A. 2014 Nov;1368:116

• 20. Liu, Mengshun, et al. "Folding fan mode counter-current chromatography offers fast blind screening for drug discovery. Case study: Finding anti-enterovirus 71 agents from Anemarrhena asphodeloides." Journal of Chromatography A 1368 (2014): 116-124.https://

• 19. Wang, Peng, et al. "Ionic liquid-based ultrasonic/microwave-assisted extraction of steroidal saponins from Dioscorea zingiberensis CH Wright."?Tropical Journal of Pharmaceutical Research?13.8 (2014): 1339-1345.https://doi.org/10.4314/tjpr.v13i8.20

• 18. Tan, Yao, et al. "Multiomics integrative analysis for discovering the potential mechanism of dioscin against hyperuricemia mice." Journal of Proteome Research 20.1 (2020): 645-660.https://doi.org/10.1021/acs.jproteome.0c00584

• 17. 馬境謙,崔乃菠,余河水,李正,劉二偉,別松濤.基于4種皂苷的定量分析評價(jià)干燥方式對菊葉薯蕷有效成分的影響[J].中南藥學(xué),2021,19(03):413-418.

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輸入產(chǎn)品批號：

本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *