• 介紹：

  Silibinin (Silibinin A) 為抗癌和化療預(yù)防化合物，能抑制細胞增殖和遷移。

• 熔點： 164-174°C

• 沸點： 793°C at 760mmHg

• 比旋光度： +8 ~ +12 ° (c=0.21in acetone at 20 °C)

• 外觀： 類白色結(jié)晶性粉末

• 溶解性： DMSO  :  250  mg/mL  (518.20  mM;  Need  ultrasonic)

• 儲存條件： 2-8℃

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

• 20. [IF=5] Wei Wang et al."Beneficial effects of silibinin on serum lipids, bile acids, and gut microbiota in methionine-choline-deficient diet-induced mice."Frontiers in Nutrition.2023; 10: 1257158

• 19. [IF=5.9] Xiaomei Zheng et al."Eriodictyol Alleviated LPS/D-GalN-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Cell Apoptosis via PI3K/AKT Signaling Pathway."Nutrients.2023 Jan;15(20):4349

• 18. [IF=6.208] Pan Wang et al."Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase: Structure–Activity Relationship and Inhibition Profiles."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(18):10747

• 17. [IF=3.246] Xu Renjie et al."Fabrication of Stable Apigenin Nanosuspension with PEG 400 as Antisolvent for Enhancing the Solubility and Bioavailability."Aaps Pharmscitech. 2022 Jan;23(1):1-11

• 16. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950

• 15. [IF=4.268] Jie Chen et al."Synergistic anti-inflammatory effects of silibinin and thymol combination on LPS-induced RAW264.7 cells by inhibition of NF-κB and MAPK activation."Phytomedicine. 2020 Nov;78:153309

• 14. [IF=11.878] Li Xinming et al."A fast and specific fluorescent probe for thioredoxin reductase that works via disulphide bond cleavage."Nat Commun. 2019 Jun;10(1):1-12

• 13. [IF=1.908] Yan Chen et al."Characterization of glutathione conjugates derived from reactive metabolites of seven silymarin isomers."Xenobiotica. 2019;49(11):1269-1278

• 12. [IF=2.977] Yan-Jiao Li et al."Silibinin exerts antidepressant effects by improving neurogenesis through BDNF/TrkB pathway."Behav Brain Res. 2018 Aug;348:184

• 11. [IF=4.5] Wang Min et al."Silibinin Prevents Autophagic Cell Death upon Oxidative Stress in Cortical Neurons and Cerebral Ischemia-Reperfusion Injury."Mol Neurobiol. 2016 Mar;53(2):932-943

• 10. Li, Fang, et al. "Lactobacillus fermentum HFY06 reduced CCl 4-induced hepatic damage in Kunming mice." RSC Advances 10.1 (2020): 1-9.https://doi.org/10.1039/C9RA08789C

• 9. Jie Chen, Dong-Li Li, Ling-Na Xie, Yu-ran Ma, Pan-Pan Wu, Chen Li, Wen-Feng Liu, Kun Zhang, Ren-Ping Zhou, Xue-Tao Xu, Xi Zheng, Xia Liu, Synergistic anti-inflammatory effects of silibinin and thymol combination on LPS-induced RAW264.7 cells by inhibition

• 8. 秦帥,吳麗麗,秦靈靈,張程斐,吳呦呦,孫伯菊,劉銅華.水飛薊賓對C2C12細胞胰島素抵抗的影響及機制研究[J].世界科學技術(shù)-中醫(yī)藥現(xiàn)代化,2020,22(10):3450-3455.

• 7. 張麗芳, 林霞, 馮星海,等. 超聲輔助有機溶劑回流提取水飛薊籽中水飛薊素工藝的優(yōu)化[J]. 中成藥, 2019, 41(001):185-188.

• 6. 鄭成鳳 潘裕添 苑小寧 等. HPLC-UV-MS法對洋薊中多酚類化合物的分析和鑒定[J]. 漳州師范學院學報(自然科學版) 2013(3):81-87.

• 5. 仲金秋, 曹玉珠, 徐宏江,等. 甘草酸二銨改善ConA致小鼠肝損傷的作用研究[J]. 天然產(chǎn)物研究與開發(fā), 2018, 30(12):60-68.

• 4. 張會芳, 楊亞琛, 張久亮,等. 油菜蜂花粉加工副產(chǎn)物多酚對小鼠急性肝損傷的保護作用[J]. 食品安全質(zhì)量檢測學報, 2018, v.9(09):59-66.

• 3. 王立, 薛冰, 劉華石,等. 水飛薊賓葡甲胺滲透泵片的制備及其釋放機制考察[J]. 中國醫(yī)藥工業(yè)雜志, 2018.

• 2. 王立, 楊碩, 馬維陽,等. 水飛薊賓控釋制劑的制備及釋放機制研究[J]. 中草藥, 2015(08):1145-1150.

• 1. 徐靜涵, 薛蕓, 王彥,等. 核殼型色譜柱-高效液相色譜法快速分離檢測水飛薊素中7種非對映異構(gòu)體[J]. 化學與生物工程, 2017, 06(v.33;No.222):69-74.

輸入產(chǎn)品批號：

本計算器可幫助您計算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *