• 熔點： 275-280°C

• 比旋光度： -115°(C=0.373, 乙醇)

• 外觀： 白色粉末

• 溶解性： 不溶于水、石油醚、苯，可溶于甲醇、乙醇。

• 儲存條件： 2-8℃

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

• 32. [3.4] Yu Wang et al."Antitumor effect of polyphyllin I (PPI) on colorectal cancer: Evidence from patient-derived organoids and Notch signaling suppression."Heliyon.2024 Sep;10:

• 31. [IF=5.6] Di Zhou et al."Establishment of a multicomponent quality control method and the transfer characteristics of five markers from Qidongning Formula to rat tissues by HPLC-QQQ-MS/MS."Frontiers in Pharmacology.2023; 14: 1310266

• 30. [IF=2.8] Peiliang Zou et al."Polyphyllin I induces ferroptosis in castration-resistant prostate cancer cells through the ERK/DNMT1/ACSL4 axis."PROSTATE.10.1002/pros.24626

• 29. [IF=7.3] Rui-Fang Dong et al."Discovery of a potent inhibitor of chaperone-mediated autophagy that targets the HSC70-LAMP2A interaction in non-small cell lung cancer therapy."BRITISH JOURNAL OF PHARMACOLOGY.2023 Jun;:

• 28. [7.382] Kaixin Wang et al."Functional metal-organic framework nanoparticles loaded with Polyphyllin I for targeted tumor therapy."Journal of Science-Advanced Materials and Devices.2023 Mar;:100548

• 27. [IF=5.062] Min Jiang et al."A novel polyphyllin I-based liposome delivery system sensitizes hepatic carcinoma to doxorubicin via cholesterol modulation."JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY.2022 Oct;:103925

• 26. [IF=4.412] Feng Su et al."Study of Chemical Compositions and Anticancer Effects of Paris polyphylla var. Chinensis Leaves."MOLECULES. 2022 Jan;27(9):2724

• 25. [IF=2.289] Zhou Shun et al."Anthelmintic efficacy of natural saponins against Gyrodactylus kobayashii in goldfish (Carassius auratus) and their 3D-QSAR analysis."Parasitol Res. 2021 Mar;120(3):1143-1150

• 24. [IF=3] Ming-Ming LIU et al."Polyphyllin I promotes cell death via suppressing UPR-mediated CHOP ubiquitination and degradation in non-small cell lung cancer."Chin J Nat Medicines. 2021 Apr;19:255

• 23. [IF=4.242] Shun Zhou et al."Anthelmintic efficacy of 35 herbal medicines against a monogenean parasite, Gyrodactylus kobayashii, infecting goldfish (Carassius auratus)."Aquaculture. 2020 May;521:734992

• 22. [IF=5.645] Bo Li et al."Organ-specific transcriptome sequencing and mining of genes involved in polyphyllin biosynthesis in Paris polyphylla."Ind Crop Prod. 2020 Nov;156:112775

• 21. [IF=2.439] Yunfei Zhang et al."Polyphyllin I inhibits growth and invasion of cisplatin-resistant gastric cancer cells by partially inhibiting CIP2A/PP2A/Akt signaling axis."J Pharmacol Sci. 2018 Jul;137:305

• 20. [IF=3.571] Xuewen Liu et al."Polyphyllin I inhibits invasion and epithelial-mesenchymal transition via CIP2A/PP2A/ERK signaling in prostate cancer."Int J Oncol. 2018 Sep;53(3):1279-1288

• 19. [IF=4.044] Feng Liu et al."Comparative analysis of proteomic and metabolomic profiles of different species of Paris."J Proteomics. 2019 May;200:11

• 18. [IF=4.072] Yan Yin et al."A cytochrome P450 monooxygenase responsible for the C-22 hydroxylation step in the Paris polyphylla steroidal saponin biosynthesis pathway."Phytochemistry. 2018 Dec;156:116

• 17. Liu, Feng, et al. "Comparative analysis of proteomic and metabolomic profiles of different species of Paris." Journal of proteomics 200 (2019): 11-27.https://doi.org/10.1016/j.jprot.2019.02.003

• 16. Liu, Feng, et al. "Comparative analysis of proteomic and metabolomic profiles of different species of Paris." Journal of proteomics 200 (2019): 11-27.https://doi.org/10.1016/j.jprot.2019.02.003

• 15. 彭鵬,金鑫,申杰,張?zhí)?向雨晨,劉瑩.重樓皂苷Ⅰ通過激活A(yù)MPK信號通路誘導(dǎo)非小細胞肺癌自噬的作用機制[J].湖北醫(yī)藥學(xué)院學(xué)報,2021,40(01):1-6+15+113.

• 14. 喻青青,樊旭,朱敏,郗雪艷,杜伯雨.重樓皂苷Ⅰ抗肝癌細胞作用的初步研究[J].中國免疫學(xué)雜志,2021,37(01):57-60+65.

• 13. 喻青青,李征遠,杜伯雨.重樓皂苷Ⅰ對肝癌細胞株Huh7、HepG2細胞增殖的影響研究[J].現(xiàn)代醫(yī)藥衛(wèi)生,2020,36(22):3551-3554.

• 12. 王仕寶 蘇瑩 李會寧 等. 響應(yīng)面法優(yōu)化重樓藥材中甾體皂苷的回流提取工藝研究[J]. 陜西農(nóng)業(yè)科學(xué) 2019 065(001):46-52.

• 11. 王仕寶 蔡艷妮 賈慧梅 等. HPLC法測定不同來源重樓藥材中7種甾體皂苷的含量[J]. 西北藥學(xué)雜志 2017 32(002):133-138.

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• 8. 向雨晨,楊銳,周彤,司淵,劉雪文,劉瑩.重樓皂苷Ⅰ通過下調(diào)CIP2A/PP2A/ERK信號通路抑制前列腺癌轉(zhuǎn)移的機制研究[J].湖北醫(yī)藥學(xué)院學(xué)報,2019,38(03):201-208.

• 7. 劉雪文,楊銳,趙紅艷,司淵,劉瑩,張?zhí)?重樓皂苷Ⅰ直接靶向STAT3抑制神經(jīng)膠質(zhì)瘤U251細胞增殖并誘導(dǎo)凋亡[J].腫瘤,2020,40(03):163-171.

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輸入產(chǎn)品批號：

本計算器可幫助您計算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *