• 介紹：

  Itraconazole是三唑類抗真菌藥，也是口服活性的Hedgehog信號(hào)通路拮抗劑，IC50約為 800 nM。它也是 oxysterol-binding protein抑制劑。它抑制羊毛甾醇 14α-脫甲基酶，從而抑制羊毛甾醇向麥角固醇的氧化轉(zhuǎn)化。它有抗癌和抗血管作用。

• 熔點(diǎn)： 166°C

• 沸點(diǎn)： 850 °C at 760 mmHg

• 比旋光度： -0.1～+0.1°(D/20℃)(c=10,CH2Cl2)

• 外觀： Solid

• 溶解性： DMSO  :  6.25  mg/mL  (8.86  mM;  Need  ultrasonic)

• 敏感性： 對(duì)熱敏感

• 儲(chǔ)存條件： 2-8℃

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

• 4. [1.3] Wenwen Xia et al."A general and rapid LC-MS/MS method for simultaneous determination of voriconazole, posaconazole, fluconazole, itraconazole and hydroxyitraconazole in IFI patients."JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS.2024 Sep;:107565

• 3. [5.4] Huan Sun et al."Dandelion Inspired Microparticles with Highly Efficient Drug Delivery to Deep Lung."COLLOIDS AND SURFACES B-BIOINTERFACES.2024 Jul;:114134

• 2. [IF=6.529] Wenping Wang et al."Itraconazole exerts anti-liver cancer potential through the Wnt, PI3K/AKT/mTOR, and ROS pathways."Biomed Pharmacother. 2020 Nov;131:110661

• 1. Wang, Wenping, et al. "Itraconazole exerts anti-liver cancer potential through the Wnt, PI3K/AKT/mTOR, and ROS pathways." Biomedicine & Pharmacotherapy 131 (2020): 110661.https://doi.org/10.1016/j.biopha.2020.110661

輸入產(chǎn)品批號(hào)：

本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *