• 產(chǎn)品描述： Ciclesonide(RPR251526) is a glucocorticoid used for the treatment of obstructive airway diseases.

• 靶點： Glucocorticoid Receptor;GlucocorticoidReceptor

• 細(xì)胞實驗： Metabolism of ciclesonide: After initial cultivation, A549 cells are washed five times with 10 ml/dish sterile PBS. An ethanolic stock solution of ciclesonide is diluted 1000-fold with assay medium to generate the initial ciclesonide concentration. The cells are incubated for 1 h in DMEM/0.1% (w/v) BSA (5 ml/dish) containing 0.02 μM ciclesonide as described above in a CO2 incubator. At the end of the incubation period, dishes are washed five times with PBS and incubated for 3, 6, or 24 h at the same conditions in 5 ml/dish fresh medium (DMEM/0.1% (w/v) BSA). At each indicated time point, the medium is removed by aspiration, 5 mM EDTA-4Na/PBS added and dishes are incubated for further 5 min. The cells are detached from the dishes and harvested. Each dish is washed five times with icechilled PBS. (Only for Reference)

• 參考文獻(xiàn)：
  1.Nonaka T, et al. BMC Pharmacol. 2007, 7:12. 2.Guo Z, et al. Am J Ther. 2006, 13(6):490-501.

• 溶解性： DMSO:54.1  mg/mL  (100  mM)    Ethanol:54.1  mg/mL  (100  mM)

• 保存條件： 2-8℃

• 配置溶液濃度參考：
  

  	1mg	5mg	10mg
  1 mM	1.849 ml	9.247 ml	18.495 ml
  5 mM	0.37 ml	1.849 ml	3.699 ml
  10 mM	0.185 ml	0.925 ml	1.849 ml
  50 mM	0.037 ml	0.185 ml	0.37 ml

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

輸入產(chǎn)品批號：

本計算器可幫助您計算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *