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• 產(chǎn)品描述： Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.

• 靶點： DopamineReceptor

• 體內(nèi)研究：
  Azaperone eliminates fighting only for a few hours after it is administered, after which the behaviour of pigs treated with it is not different from that of non-tranquillized mixed pigs. Azaperone (2.2 mg/kg i.m.) reduces total fighting from 309.8 min for saline to 189.6 min in pigs. Azaperone (103.1 mg) combined with Butorphanol (69.3 mg) produces adequate muscle relaxation and apparently adequate analgesia for minor surgical interferences, including abdominal laparoscopy, in a white rhinoceros with chronic renal disease. Azaperone combined with Butorphanol and Medetomidine (BAM: 0.43 mg/kg Butorphanol, 0.36 mg/kg Azaperone, 0.14 mg/kg Medetomidine) results in a predictable onset of sedation, with a mean induction time to lateral recumbency of 9.8 min, in white-tailed deer. Azaperone combined with Butorphanol and Medetomidine (BAM: 0.43 mg/kg Butorphanol, 0.36 mg/kg Azaperone, 0.14 mg/kg Medetomidine) results in decreased heart rate and increased arterial partial pressure of carbon dioxide (PaCO2) in white-tailed deer. Azaperone (1.0 mg/kg) combined with Ketamine (15 mg/kg) and Climazolam (1.5 mg/kg) results in a significantly higher castration score, when administrated intranasally (IN) compared with intramuscularly (IM) in piglets, there is an association between castration score and room temperature in the IN group. Azaperone (1.0 mg/kg) combined with Ketamine (15 mg/kg) and Climazolam (1.5 mg/kg) results in higher heart rate in the IN group of piglets. Azaperone (1.0 mg/kg) combined with Ketami

• 參考文獻：
  1. Axiak SM, et al. Schweiz Arch Tierheilkd, 2007, 149(9), 395-402. 2. Radcliffe RW, et al. J Zoo Wildl Med, 2000, 31(2), 196-200. 3. SSL Tan, et al. Appl Anim Behav Sci, 1990, 26(1-2), 157-168. 4. Mich PM, et al. J Zoo Wildl Med, 2008, 39(3), 480-487. 5.Gonyou HW, et al. J Anim Sci, 1988, 66(11), 2856-2864.

• 溶解性： Soluble  in  DMSO、Ethanol

• 保存條件： 2-8℃

• 配置溶液濃度參考：
  

  	1mg	5mg	10mg
  1 mM	3.054 ml	15.272 ml	30.544 ml
  5 mM	0.611 ml	3.054 ml	6.109 ml
  10 mM	0.305 ml	1.527 ml	3.054 ml
  50 mM	0.061 ml	0.305 ml	0.611 ml

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

輸入產(chǎn)品批號：

本計算器可幫助您計算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *