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• 產(chǎn)品描述： IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6).

• 靶點(diǎn)： PAK

• 細(xì)胞實(shí)驗(yàn)： Human primary schwannoma cells are grown on 96 well plates for 2 days. Cells are left untreated or treated with 5 μM IPA-3, 20 μM IPA-3 or 20 μM PIR-3.5 for 24 hours. The MTS-solution is left on the cells for 3 hours, before the absorbance at 490 nm is measured. The experiments are conducted three times and mean and standard error of the mean is calculated with Excel.

• 參考文獻(xiàn)：
  1. Deacon SW, et al. Chem Biol, 2008, 15(4), 322-331. 2. Viaud J, et al. Mol Cancer Ther, 2009, 8(9), 2559-2565.

• 溶解性： Soluble  in  DMSO、Ethanol

• 保存條件： 2-8℃;避光

• 配置溶液濃度參考：
  

  	1mg	5mg	10mg
  1 mM	2.853 ml	14.267 ml	28.535 ml
  5 mM	0.571 ml	2.853 ml	5.707 ml
  10 mM	0.285 ml	1.427 ml	2.853 ml
  50 mM	0.057 ml	0.285 ml	0.571 ml

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

輸入產(chǎn)品批號(hào)：

本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *