S80778 |
Sulfaphenazole |
源葉(MedMol) | 99% |
- 提示:詳情請下載說明書。
- 產品描述: Sulfaphenazole is a specific inhibitor of CYP2C9 which blocks atherogenic and pro-inflammatory effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Acts as an antibacterial and antimicrobial.
- 靶點: Bacterial;P450;Antibacterial
- 參考文獻:
1. Chimalakonda KC, et al. Sulfaphenazole and α-naphthoflavone attenuate the metabolism of the synthetic cannabinoids JWH-018 and AM2201 found in K2/spice. Drug Metab Lett. 2013 Mar;7(1):34-8. 2. Hama S, et al. Effects of sulfaphenazole after collagenase-induced experimental intracerebral hemorrhage in rats. Biol Pharm Bull. 2012;35(10):1849-53. 3. BROWNE SG.Trial of a long-acting sulfonamide sulfaphenazole (Orisul, Ciba), in the treatment of leprosy. Int J Lepr. 1961 Oct-Dec;29:502-5.
- 溶解性: DMSO : ≥ 100 mg/mL (318.11 mM)
- 保存條件: 2-8℃
- 配置溶液濃度參考:
1mg 5mg 10mg 1 mM 3.181 ml 15.905 ml 31.811 ml 5 mM 0.636 ml 3.181 ml 6.362 ml 10 mM 0.318 ml 1.591 ml 3.181 ml 50 mM 0.064 ml 0.318 ml 0.636 ml
- 注意:部分產品我司僅能提供部分信息,我司不保證所提供信息的權威性,僅供客戶參考交流研究之用。
- 2. 陳瑞,周維,張麗,朱高峰,黃靜,湯磊.樹豆酮酸A對人肝微粒體中5種常見細胞色素P_(450)酶的體外抑制作用研究[J].中國藥房,2021,32(02):195-200.
- 1. 王呈諭,李登科,全正揚,胡英還,孫震曉.基于細胞色素氧化酶CYP2D6的何首烏肝細胞毒性及相關成分研究[J].中國藥物警戒,2021,18(03):220-227+239.
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本計算器可幫助您計算出特定溶液中溶質的質量、溶液濃度和體積之間的關系,公式為:
質量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)