S81267 |
Netarsudil (AR-13324) 2HCl |
源葉(MedMol) | 99% |
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- 產(chǎn)品描述: Netarsudil Dihydrochloride is an inhibitor of Rho-associated protein kinase (ROCK) and norepinephrine transporter (NET) with effective in intraocular pressure (IOP) reduction.
- 靶點(diǎn): ROCK
- 體內(nèi)研究:
Netarsudil Dihydrochloride (AR-13324 Dihydrochloride; 0.04%, 50 ΜL)reduces intraocular pressure (IOP) in normotensive monkey eyes. Netarsudil Dihydrochloride (0.04%) produces a statistically significant lowering of episcleral venous pressure (EVP) in Dutch Belted rabbits
- 參考文獻(xiàn):
1. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-54. 2.Kiel JW, et al. Effect of AR-13324 on episcleral venous pressure in Dutch belted rabbits. J Ocul Pharmacol Ther. 2015 Apr;31(3):146-151.
- 溶解性: Soluble in DMSO
- 保存條件: -20℃
- 配置溶液濃度參考:
1mg 5mg 10mg 1 mM 0 ml 0 ml 0 ml 5 mM 0 ml 0 ml 0 ml 10 mM 0 ml 0 ml 0 ml 50 mM 0 ml 0 ml 0 ml
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輸入產(chǎn)品批號(hào):
本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系,公式為:
質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)