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S84399

Farampator

源葉(MedMol) 98%
  • 英文名:
  • Farampator
  • 別名:
  • Farampator; CX-691; UNII-7X6P5N8K2L;
  • CAS號(hào):
  • 211735-76-1
  • 分子式:
  • C12H13N3O2
  • 分子量:
  • 231.25
  • 核磁/質(zhì)譜:
品牌貨號(hào)產(chǎn)品規(guī)格價(jià)格(RMB) 庫(kù)存(上海) 北京 武漢 南京 數(shù)量計(jì)量單位 加入購(gòu)物車(chē)...
源葉(MedMol) S84399-2mg 98% ¥278.80元 5 - - - EA 加入購(gòu)物車(chē)
源葉(MedMol) S84399-5mg 98% ¥510.00元 6 - - - EA 加入購(gòu)物車(chē)
源葉(MedMol) S84399-10mg 98% ¥714.00元 6 - - - EA 加入購(gòu)物車(chē)
源葉(MedMol) S84399-25mg 98% ¥1360.00元 5 - - - EA 加入購(gòu)物車(chē)
源葉(MedMol) S84399-50mg 98% ¥2244.00元 預(yù)計(jì)交期:2-3天 - - - EA 加入購(gòu)物車(chē)
源葉(MedMol) S84399-100mg 98% ¥4012.00元 預(yù)計(jì)交期:2-3天 - - - EA 加入購(gòu)物車(chē)
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產(chǎn)品介紹

參考文獻(xiàn)

質(zhì)檢證書(shū)(COA)

摩爾濃度計(jì)算器

相關(guān)產(chǎn)品

  • 提示:詳情請(qǐng)下載說(shuō)明書(shū)。
  • 產(chǎn)品描述: Farampator (CX-691;Org24448) is a positive modulator of AMPA receptor.
  • 靶點(diǎn): GluR;iGluR;GluR;?iGluR
  • 體內(nèi)研究:
    Farampator has potential in treating disorders characterised by cognitive deficits such as Alzheimer's disease and schizophrenia. CX691 attenuates a scopolamine-induced impairment of cued fear conditioning following acute administration (0.1 mg/kg p.o.) and a temporally induced deficit in novel object recognition following both acute (0.1 and 1.0 mg/kg p.o.) and sub-chronic (bi-daily for 7 days) administration (0.01, 0.03, 0.1 mg/kg p.o.). It also improves attentional set-shifting following sub-chronic administration (0.3 mg/kg p.o.)[1]. Farampator (500 mg) unequivocally improves short-term memory but appeares to impair episodic memory. Besides, it tends to decrease the number of switching errors in the CTMT. Drug-induced side effects (SEs) included headache, somnolence and nausea. Subjects with SEs has significantly higher plasma levels of farampator than subjects without SEs
  • 參考文獻(xiàn):
    1.Woolley ML, et al. Evaluation of the pro-cognitive effects of the AMPA receptor positive modulator, 5-(1-piperidinylcarbonyl)-2,1,3-benzoxadiazole (CX691), in the rat. Psychopharmacology (Berl). 2009 Jan;202(1-3):343-54. 2.Wezenberg E, et al. Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers. Neuropsychopharmacology. 2007 Jun;32(6):1272-83.
  • 溶解性: DMSO:34  mg/mL
  • 保存條件: 2-8℃
  • 配置溶液濃度參考:
    1mg 5mg 10mg
    1 mM 4.324 ml 21.622 ml 43.243 ml
    5 mM 0.865 ml 4.324 ml 8.649 ml
    10 mM 0.432 ml 2.162 ml 4.324 ml
    50 mM 0.086 ml 0.432 ml 0.865 ml
  • 注意:部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權(quán)威性,僅供客戶(hù)參考交流研究之用。
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